Job Summary Table of Molecular Virology

Molecular Virology Research Opportunity: Job Description Summary

The Sheppard Lab within Imperial College London’s Department of Infectious Disease is seeking a highly motivated Research Associate to investigate critical host-pathogen interactions affecting influenza virus infection. This MRC-funded position offers the unique opportunity to characterize how host proteins influence the influenza RNA polymerase, ultimately contributing to the development of novel antiviral strategies.

Key Responsibilities in Virology Research

• 🔬 Lead a pioneering proximity proteomics approach to comprehensively map host proteins interacting with the influenza RNA polymerase, working collaboratively with proteomics experts at King’s College London
• 🧪 Develop and optimize systematic workflows to identify, validate, and conduct bioinformatic analyses of host factors regulating polymerase function across diverse influenza subtypes
• 🦠 Employ multidisciplinary techniques including gene editing, functional and binding reporter assays, viral growth kinetics, and cross-linking mass spectrometry (XL-MS)
• 🔍 Conduct detailed structure-function characterization of key virulence factors to inform the development of novel antiviral therapeutics
• 📊 Analyze and interpret complex experimental data to identify promising follow-up strategies and research directions
• 📝 Prepare manuscripts for publication in peer-reviewed journals and present findings at national and international conferences
• 👥 Collaborate closely with the Barclay lab and other research groups to translate findings into practical antiviral applications

Benefits and Perks of Research at Imperial

• 🏆 World-class research environment at a global top ten university with cutting-edge facilities
• 🔬 Access to advanced laboratory infrastructure including CL2/CL3 tissue culture suites, proteomics platforms, and FACS systems
• 🌐 Interdisciplinary collaboration opportunities with leading groups in virology, immunology, and systems biology
• ✈️ Conference travel support to showcase your work and expand your professional network
• 📈 Career development mentorship including guidance on grant writing and academic progression
• 📆 Generous leave allowance of 39 days off per year (including public holidays)
• 💰 Competitive pension scheme as part of a comprehensive remuneration package
• 🧠 Access to Imperial’s sector-leading career support for researchers and opportunities for promotion

Research Environment and Company Overview

Imperial College London stands among the world’s top universities, where scientific innovation drives transformative impact across disciplines. With a vibrant community of 22,000 students and 8,000 staff collaborating across nine London campuses and international networks, Imperial tackles some of humanity’s most pressing challenges—from global health to climate change and artificial intelligence.

The Sheppard Lab specifically focuses on host-pathogen interactions with emphasis on viral mechanisms that impact human health. Their current MRC-funded project aims to uncover the molecular intricacies of how host proteins influence influenza virus infection, with the ultimate goal of informing next-generation antiviral therapeutic strategies.

Molecular Virology Research Culture at Imperial

The laboratory environment prioritizes both scientific excellence and team cohesion, fostering an inclusive atmosphere where rigorous research thrives alongside collaborative problem-solving. The Department of Infectious Disease maintains a dynamic research ecosystem where interdisciplinary approaches are encouraged, connecting virologists with immunologists, systems biologists, and clinicians.

Imperial College London’s core values of respect, collaboration, excellence, integrity, and innovation permeate all aspects of the research culture. The institution actively promotes work-life balance while maintaining its position at the forefront of scientific discovery.

Career Growth Opportunities in Virology Research

This position offers exceptional opportunities for professional advancement within molecular virology and broader biomedical research. As a Research Associate, you’ll receive:

• Structured mentorship in scientific writing, grant preparation, and career planning
• Clear pathways for progression within Imperial’s academic framework
• Networking opportunities with international leaders in virology and infectious disease
• Skills development workshops tailored to researchers at your career stage
• Experience with cutting-edge techniques that enhance employability across academic and industry sectors

Diversity, Equity, Inclusion, and Belonging

Imperial College London is committed to creating an environment where diversity is celebrated and everyone feels valued and respected. The institution works actively toward equality of opportunity, eliminating discrimination, and fostering an inclusive workplace. Applications are encouraged from all backgrounds, communities, and industries, reflecting Imperial’s commitment to building diverse teams with varied skills, experiences, and perspectives.

Equal Opportunity Statement in Research Recruitment

Imperial College London is an equal opportunity employer committed to building a culturally diverse community. The institution encourages applications from underrepresented groups and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic.

Laboratory On-Site Work Policy

This full-time, fixed-term (3 years) position requires on-site presence at the South Kensington Campus. Given the specialized nature of laboratory-based virology research, including work with biological agents in controlled environments, remote work options are not available for this role. However, the laboratory maintains flexible working hours where possible within the constraints of experimental protocols.

Application Process for Virology Researchers

1. Review the full job description available in PDF format on the Imperial College London jobs portal
2. Prepare your application materials including CV, cover letter, and research statement
3. Submit your application through the online portal at Imperial College London’s website
4. Participate in interview process if shortlisted, potentially including a presentation of past research

Application Deadline for Research Position

Applications must be submitted by June 16, 2025. However, Imperial College London reserves the right to close the advertisement early if a sufficient number of suitable applications are received.

How to Apply for Research Associate Position

For complete application instructions and to submit your materials, visit the official job posting. For specific questions about the position, contact Dr. Carol Sheppard at carol.sheppard08@imperial.ac.uk.

If you encounter technical difficulties during the application process, contact the support team at support.jobs@imperial.ac.uk.

Social Media Links

Connect with Imperial College London: – LinkedIn – Twitter – Facebook

FAQs for Molecular Virology Position

Q: Is a completed PhD required at the time of application?
A: Candidates who have not yet officially been awarded their PhD will be appointed as a Research Assistant with a salary range of £43,003 – £46,297 per annum until completion of their doctorate.

Q: What specific skills are considered most valuable for this position?
A: Experience with cell culture, molecular cloning, viral rescue/growth, gene-silencing, protein-protein interactions, and mass spectrometry techniques are particularly relevant.

Q: Is relocation assistance provided?
A: For specific information about relocation support, please contact the hiring manager directly.

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