Job Summary Table of PhD Studentship: Breast Cancer Research at Nottingham

Job Description Summary

This PhD studentship offers a unique opportunity to join a world-class research team at the University of Nottingham, focusing on the development and application of recombinant antibodies to map pathology-related changes in glycosaminoglycans on breast cancer cells.

Responsibilities

• Isolate a range of recombinant antibodies that bind to glycosaminoglycans (GAGs)
• Utilize next generation phage display (NGPD) technology to target cell surface GAGs from breast cancer cell populations
• Identify specific binders, clone and express them
• Characterize binding against breast cancer cell populations and defined GAG structures
• Collaborate with research groups from various institutions and international partners
• Contribute to the BBSRC strategic Longer and Larger project, GlycoWeb

Benefits and Perks

• Fully funded studentship for UK nationals
• Opportunity to work with cutting-edge technologies in antibody research
• Collaboration with world-renowned research institutions
• Potential for international travel and networking opportunities
• Access to state-of-the-art research facilities at the University of Nottingham

Company Overview

The University of Nottingham is a world-class institution known for its excellence in research and education. The School of Veterinary Medicine and Science, where this studentship is based, undertakes a wide range of research from fundamental biology to population studies, integrated into the University’s structure with established world-class research in biomedical sciences.

Company Culture

🔬 At the University of Nottingham, we foster a collaborative and innovative research environment. Our culture is characterized by:

• Interdisciplinary collaboration
• Cutting-edge research initiatives
• Support for early-career researchers
• Emphasis on scientific excellence and integrity

Career Growth Opportunities

📈 This PhD studentship offers exceptional career growth opportunities:

• Develop expertise in advanced antibody research techniques
• Gain experience in a highly relevant field of cancer research
• Build a network of contacts in academia and industry
• Potential for publication in high-impact scientific journals
• Lay the foundation for a successful career in biomedical research or related fields

Diversity, Equity, Inclusion, and Belonging

🌈 The University of Nottingham is committed to fostering a diverse and inclusive research environment. We welcome applications from candidates of all backgrounds and strive to create an equitable and supportive atmosphere for all our researchers.

Equal Opportunity Statement

The University of Nottingham is an equal opportunity employer. We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law.

Remote Work Policy

🏢 This PhD studentship requires on-site presence at the University of Nottingham. However, there may be opportunities for occasional remote work or collaboration with international partners, depending on the project’s needs.

Application Process

1. Review the eligibility criteria and project description
2. Prepare your CV and any required documents
3. Apply online through the University of Nottingham’s application portal
4. Send your student ID number to SV-PG-VET@exmail.nottingham.ac.uk after submission

Application Deadline

The position will be filled when suitable candidates have been identified. Early application is strongly encouraged.

How to Apply

🔗 To apply for this exciting opportunity:

1. Visit the University of Nottingham job portal
2. Complete the online application form
3. Select the School of Veterinary Medicine and Science
4. Choose PhD Molecular Medicine (and Complex Diseases) (48m)
5. Submit your application and send your student ID number to SV-PG-VET@exmail.nottingham.ac.uk

For any queries regarding the application process, please contact SV-PG-VET@exmail.nottingham.ac.uk.

Social Media Links

• University of Nottingham LinkedIn
• University of Nottingham Twitter
• University of Nottingham Facebook

FAQs or Additional Information

What is the project’s focus?

The project aims to develop and apply recombinant antibodies to map pathology-related changes in glycosaminoglycans on breast cancer cells. This research is part of the larger BBSRC strategic Longer and Larger project, GlycoWeb.

Who are the supervisors?

The principal supervisor is Professor Kevin Gough. Other supervisors include Professor Cathy Merry, Dr. Cinzia Allegrucci, Dr. Jennifer Ashworth, and Dr. Kieran Pitchers.

What techniques will I learn?

You will gain expertise in antibody phage display technology, next generation sequencing, and characterization of antibody binding against cancer cell populations and defined GAG structures.

Are there opportunities for collaboration?

Yes, you will be part of an extensive team including research groups from The University of Nottingham, Liverpool University, Manchester University, and the Francis Crick Institute, alongside international and commercial partners.

When does the studentship start?

The start date is December 1st or as soon as possible thereafter.

This PhD studentship presents an exceptional opportunity for ambitious researchers to contribute to groundbreaking breast cancer research. By joining the University of Nottingham’s world-class team, you’ll be at the forefront of developing novel tools for detecting and characterizing glycosaminoglycans in cancer tissues. This project not only offers the chance to work with cutting-edge technologies but also provides a platform for significant scientific impact and career growth.

The interdisciplinary nature of the GlycoWeb project ensures exposure to a wide range of scientific expertise and methodologies. You’ll have the unique opportunity to collaborate with leading researchers from multiple institutions, fostering a rich learning environment and building a robust professional network.

If you’re passionate about making a difference in cancer research and eager to develop advanced skills in antibody engineering and cell biology, this studentship could be the perfect launchpad for your scientific career. Don’t miss this chance to be part of a project that could revolutionize our understanding of breast cancer pathology and potentially lead to new diagnostic or therapeutic approaches.

Apply now to embark on this exciting journey in biomedical research at one of the UK’s top universities. Your contribution could be the key to unlocking new insights in the fight against breast cancer.

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